Organic phosphoric acids and derivatives
Selleck Chemical LLC Antazoline Phosphate
Antazoline Phosphate is the phosphate salt of antazoline Antazoline is a first-generation antihistaminic agent and acts as a histamine H1 receptor antagonist
Medchemexpress LLC Trisodium phosphate | 7601-54-9 | MFCD00003510 | 99.5% | 163.94 g/mol | Na3PO4 | 1kg
Trisodium phosphate is a food additive Trisodium phosphate affects the growth parameters (lag phase maximum growth rate) of Listeria monocytogenes and increases the sensitivity of Gram-negative bacteria to Lysozyme (HY-P1068) and Nisin (HY-P1607)[1][2]
Medchemexpress LLC Diethyl 2-bromoglutarate | 7209-00-9 | 91.0% | 267.12 | 10 G
Diethyl 2-bromoglutarate is a drug intermediate for the synthesis of various active compounds. It is for research use only and not sold to patients.
- Drug intermediate for synthesis of various active compounds
- Appearance: Liquid
- Color: Colorless to light yellow
Medchemexpress LLC FTY720 (S)-Phosphate | 402616-26-6 | C19H34NO5P | 25 MG
FTY720 (S)-Phosphate | 402616-26-6 | C19H34NO5P | 25 MG
Medchemexpress LLC Disodium phosphate | 7558-79-4 | MFCD00003496 | 99.0% | 141.96 g/mol | HNa2O4P | 100g
Disodium phosphate is commonly used as a food additive buffer and laboratory reagent Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers detergents and water treatment products Additionally it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 10mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Medchemexpress LLC Dihexadecyl hydrogen 500mg
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids It s often used as an emulsifier which means it helps mix two substances together that don t usually mix well such as oil and water Dihexadecyl hydrogen phosphateIt has several applications in the food industry especially in the production of processed foods where it improves texture and stability Additionally it has applications in the pharmaceutical industry where it can be used ain the generation of micelles liposomes and other types of artificial membranes
Medchemexpress LLC KN-92 phosphate | 1135280-28-2 | MFCD24369012 | 99.7% | 554.98 | C24H28ClN2O7PS | 10 MG
KN-92 phosphate is the inactive phosphate derivative of a CaMKII inhibitor, provided as a white to off-white solid for use as a control compound in biochemical and cellular studies. It is characterized by high purity and defined physicochemical properties, with limited water solubility and recommended sealed storage away from moisture.
- Intended as a negative control for studies of CaMKII activity.
- High purity (~99.7%) suitable for research applications.
- Molecular weight 554.98; formula C24H28ClN2O7PS.
- Low solubility in water; soluble in DMSO (50 mg/mL).
- Packaged as a 10 mg quantity for laboratory use.
- For research use only; not intended for human use.
Medchemexpress LLC Sodium phosphate dibasic | 7558-79-4 | 99.2% | 141.96 | Na2HPO4 | 10g
Sodium phosphate dibasic (Disodium hydrogen phosphate) for cell culture is a buffer and chelating agent Sodium phosphate dibasic is used to adjust the pH of liquids Sodium phosphate dibasic can be used in cell culture[1]
Apexbio Technology LLC Carvedilol Phosphate 610309-89-2 25g
Carvedilol phosphate (CAS 610309-89-2) is a non-selective beta-adrenoceptor and alpha-1 receptor antagonist targeting adrenergic receptors It is designed to inhibit sympathetic nervous system signaling thereby regulating cardiovascular function and suppressing lipid peroxidation Carvedilol phosphate exerts its biological activity primarily through blockade of beta and alpha-1 adrenergic receptors and inhibition of lipid peroxidation In in vitro studies carvedilol phosphate demonstrates autophagy induction and inhibition of NLRP3 inflammasome activation with reported IC50 values for beta-adrenergic blockade typically in the nanomolar-to-low micromolar range depending on receptor subtype and assay conditions Based on these pharmacological properties carvedilol phosphate holds research potential in hypertension congestive heart failure myocardial ischemia and inflammatory response studies
Medchemexpress LLC 2-propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-, (2E)- | 18550-98-6 | 98.95% | 210.23 | 100 MG
3PO, also known as 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-, (2E)-, is a potent inhibitor of PFKFB3. This compound effectively attenuates the proliferation of various cancer cell lines by suppressing glucose uptake and reducing the intracellular concentrations of key metabolic intermediates like Fru-2,6-BP, lactate, ATP, NAD+, and NADH. It is commonly utilized in cancer research for its role in influencing cell cycle and inhibiting glycolytic flux.
- Inhibits PFKFB3, a key enzyme in glycolysis.
- Attenuates proliferation of multiple cancer cell lines.
- Suppresses cellular glucose uptake.
- Decreases intracellular concentrations of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.
- Induces G2-M phase cell cycle arrest in certain cell types.
- Used extensively in cancer research studies.
- Demonstrates activity in both in vitro and in vivo models.
Medchemexpress LLC Kn-93 phosphate | 1913269-12-1 | 99.7% | 599.03 g·mol⁻¹ | C26H32ClN2O8PS | 10 MG
KN-93 phosphate is the phosphate salt form of KN-93, a cell-permeable, reversible, competitive inhibitor of calmodulin-dependent kinase II (CaMKII) with a reported Ki of 370 nM. It is provided as a high-purity research reagent intended for in vitro and cell-based studies investigating CaMKII signaling pathways.
- High purity suitable for research applications.
- Water-soluble phosphate salt for improved solubility in aqueous assays.
- Reported Ki of 370 nM against CaMKII for potency reference.
- Available in small pack sizes to support screening and optimization.
- Provided with analytical data supporting quality and identity.
Medchemexpress LLC Disodium hydrogen phosphate anhydrous | 7558-79-4 | MFCD00003496 | 99.0% | 141.96 g/mol | Na2HPO4 | 1g
Disodium phosphate is commonly used as a food additive buffer and laboratory reagent Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers detergents and water treatment products Additionally it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions
Medchemexpress LLC Diethyl pyrocarbonate | 1609-47-8 | 99.3% | 50 G
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. It has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate also inhibits central chemosensitivity in rabbits and can modify Ser, Thr, His, and Tyr residues. It can be utilized for modeling purposes.
- Potent and orally active.
- Non-specific chemical inhibitor of RNase.
- Relatively specific for binding to imidazole of histidine in vitro.
- Inhibits central chemosensitivity.
- Modifies Ser, Thr, His, and Tyr residues.
- Can be used for modeling.